Method for the preparation of a viral vector by inter-molecular homologous recombination

The present invention encompasses methods of preparing a recombinant viral vector, within a procaryotic cell, by intermolecular homologous recombination, methods of preparing an infectious viral particle containing the recombinant viral vector and pharmaceutical compositions comprising said vector o...

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Hauptverfasser: CHARTIER CECILE, DEGRYSE ERIC
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention encompasses methods of preparing a recombinant viral vector, within a procaryotic cell, by intermolecular homologous recombination, methods of preparing an infectious viral particle containing the recombinant viral vector and pharmaceutical compositions comprising said vector or particle. The invention also encompasses the therapeutic use of said vector or particle, especially in human gene therapy.