Injectable ready-to-use solutions containing an antitumor anthracycline glycoside

According to the invention there is provided a sterile, pyrogen-free, ready-to-use solution of an anthracycline glycoside, especially doxorubicin, which consists essentially of a physiologically acceptable salt of an anthracycline glycoside dissolved in a physiologically acceptable solvent therefor,...

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Hauptverfasser: GATTI GAETANO, OLDANI DIEGO, GAMBINI LUCIANO, DE PONTI ROBERTO, BOTTONI GIUSEPPE, CONFALONIERI CARLO
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creator GATTI GAETANO
OLDANI DIEGO
GAMBINI LUCIANO
DE PONTI ROBERTO
BOTTONI GIUSEPPE
CONFALONIERI CARLO
description According to the invention there is provided a sterile, pyrogen-free, ready-to-use solution of an anthracycline glycoside, especially doxorubicin, which consists essentially of a physiologically acceptable salt of an anthracycline glycoside dissolved in a physiologically acceptable solvent therefor, which has not been reconstituted from a lyophilizate and which has a pH of from 2.5 to 6.5. The solution of the invention is particularly advantageous for the administration by injection of the anthracycline glycoside drugs. e.g. doxorubicin, in the treatment of both human and animal tumors.
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subjects CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SUGARS
title Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
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