Method of selection of a population or subpopulation of a sample utilizing particles and gravity sedimentation
A separation procedure for separating a selected desired or undesired population from a biological sample utilizing relatively heavy, dense particles and gravity sedimentation. The particles have one or more reactants bound thereto which are specific to and will bind with the selected population. Th...
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | RUSSELL THOMAS R SCHMITTLING ROBERT J COULTER WALLACE H ZWERNER ROBERT K |
| description | A separation procedure for separating a selected desired or undesired population from a biological sample utilizing relatively heavy, dense particles and gravity sedimentation. The particles have one or more reactants bound thereto which are specific to and will bind with the selected population. The particles preferably are mixed with the sample by repeatedly causing the particles to settle through a substantial portion of the sample to bind to the selected population. The particles with the bound selected population then are allowed to preferentially settle in the sample and the supernatant including an enriched population is separated from the particles with the selected population bound thereto. The enriched populations in the biological sample supernatant can be further enriched by multiple removal steps. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US6900029B1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US6900029B1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US6900029B13</originalsourceid><addsrcrecordid>eNqNjLEKAjEQRNNYiPoP-wNCVBCuVRQbK7U-1mTvbiGXhGQj6NfrqYWl1fCGNzNW_kjSBQuhgUyOjHDwAyDEEIvDDyfI5fpbDELGPjqCIuz4wb6FiEnYOMqA3kKb8MZyf91a7snLezlVowZdptk3Jwr2u_P2MKcYasoRDXmS-nJaV1rrZbVZrP5QnnhqQvc</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Method of selection of a population or subpopulation of a sample utilizing particles and gravity sedimentation</title><source>esp@cenet</source><creator>RUSSELL THOMAS R ; SCHMITTLING ROBERT J ; COULTER WALLACE H ; ZWERNER ROBERT K</creator><creatorcontrib>RUSSELL THOMAS R ; SCHMITTLING ROBERT J ; COULTER WALLACE H ; ZWERNER ROBERT K</creatorcontrib><description>A separation procedure for separating a selected desired or undesired population from a biological sample utilizing relatively heavy, dense particles and gravity sedimentation. The particles have one or more reactants bound thereto which are specific to and will bind with the selected population. The particles preferably are mixed with the sample by repeatedly causing the particles to settle through a substantial portion of the sample to bind to the selected population. The particles with the bound selected population then are allowed to preferentially settle in the sample and the supernatant including an enriched population is separated from the particles with the selected population bound thereto. The enriched populations in the biological sample supernatant can be further enriched by multiple removal steps.</description><edition>7</edition><language>eng</language><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; PERFORMING OPERATIONS ; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL ; PHYSICS ; SEPARATION ; TESTING ; TRANSPORTING</subject><creationdate>2005</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050531&DB=EPODOC&CC=US&NR=6900029B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050531&DB=EPODOC&CC=US&NR=6900029B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>RUSSELL THOMAS R</creatorcontrib><creatorcontrib>SCHMITTLING ROBERT J</creatorcontrib><creatorcontrib>COULTER WALLACE H</creatorcontrib><creatorcontrib>ZWERNER ROBERT K</creatorcontrib><title>Method of selection of a population or subpopulation of a sample utilizing particles and gravity sedimentation</title><description>A separation procedure for separating a selected desired or undesired population from a biological sample utilizing relatively heavy, dense particles and gravity sedimentation. The particles have one or more reactants bound thereto which are specific to and will bind with the selected population. The particles preferably are mixed with the sample by repeatedly causing the particles to settle through a substantial portion of the sample to bind to the selected population. The particles with the bound selected population then are allowed to preferentially settle in the sample and the supernatant including an enriched population is separated from the particles with the selected population bound thereto. The enriched populations in the biological sample supernatant can be further enriched by multiple removal steps.</description><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>PERFORMING OPERATIONS</subject><subject>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</subject><subject>PHYSICS</subject><subject>SEPARATION</subject><subject>TESTING</subject><subject>TRANSPORTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2005</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjLEKAjEQRNNYiPoP-wNCVBCuVRQbK7U-1mTvbiGXhGQj6NfrqYWl1fCGNzNW_kjSBQuhgUyOjHDwAyDEEIvDDyfI5fpbDELGPjqCIuz4wb6FiEnYOMqA3kKb8MZyf91a7snLezlVowZdptk3Jwr2u_P2MKcYasoRDXmS-nJaV1rrZbVZrP5QnnhqQvc</recordid><startdate>20050531</startdate><enddate>20050531</enddate><creator>RUSSELL THOMAS R</creator><creator>SCHMITTLING ROBERT J</creator><creator>COULTER WALLACE H</creator><creator>ZWERNER ROBERT K</creator><scope>EVB</scope></search><sort><creationdate>20050531</creationdate><title>Method of selection of a population or subpopulation of a sample utilizing particles and gravity sedimentation</title><author>RUSSELL THOMAS R ; SCHMITTLING ROBERT J ; COULTER WALLACE H ; ZWERNER ROBERT K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US6900029B13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2005</creationdate><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>PERFORMING OPERATIONS</topic><topic>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</topic><topic>PHYSICS</topic><topic>SEPARATION</topic><topic>TESTING</topic><topic>TRANSPORTING</topic><toplevel>online_resources</toplevel><creatorcontrib>RUSSELL THOMAS R</creatorcontrib><creatorcontrib>SCHMITTLING ROBERT J</creatorcontrib><creatorcontrib>COULTER WALLACE H</creatorcontrib><creatorcontrib>ZWERNER ROBERT K</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>RUSSELL THOMAS R</au><au>SCHMITTLING ROBERT J</au><au>COULTER WALLACE H</au><au>ZWERNER ROBERT K</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Method of selection of a population or subpopulation of a sample utilizing particles and gravity sedimentation</title><date>2005-05-31</date><risdate>2005</risdate><abstract>A separation procedure for separating a selected desired or undesired population from a biological sample utilizing relatively heavy, dense particles and gravity sedimentation. The particles have one or more reactants bound thereto which are specific to and will bind with the selected population. The particles preferably are mixed with the sample by repeatedly causing the particles to settle through a substantial portion of the sample to bind to the selected population. The particles with the bound selected population then are allowed to preferentially settle in the sample and the supernatant including an enriched population is separated from the particles with the selected population bound thereto. The enriched populations in the biological sample supernatant can be further enriched by multiple removal steps.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_US6900029B1 |
| source | esp@cenet |
| subjects | INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PHYSICS SEPARATION TESTING TRANSPORTING |
| title | Method of selection of a population or subpopulation of a sample utilizing particles and gravity sedimentation |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T04%3A09%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=RUSSELL%20THOMAS%20R&rft.date=2005-05-31&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS6900029B1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |