Modified proteinase inhibitors

The invention relates to proteinase inhibitors and in particular cystatins which have been modified so as to enhance the effectiveness of synthetically manufactured counterparts. The modifications include either site-directed alterations in the structure of the protein and/or the production of hybri...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MCPHERSON MICHAEL JOHN, URWIN PETER EDWARD, ATKINSON HOWARD JOHN
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to proteinase inhibitors and in particular cystatins which have been modified so as to enhance the effectiveness of synthetically manufactured counterparts. The modifications include either site-directed alterations in the structure of the protein and/or the production of hybrid molecules.