Pump as a pressure source for supercritical fluid chromatography involving pressure regulators and a precision orifice

Pump as a pressure source for supercritical fluid chromatography involving pressure regulators and a precision orifice

The invention is a device and method in a high-pressure chromatography system, such as a supercritical fluid chromatography (SFC) system, that uses a pump as a pressure source for precision pumping of a compressible fluid. The preferred exemplary embodiment comprises a pressure regulation assembly i...

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Hauptverfasser: NICKERSON MARK, KLEIN KENNETH, BENTE, III PAUL F, FOGELMAN KIMBER D, STAATS, III L. THOMPSON, BERGER TERRY A
Format: Patent
Sprache:eng
Schlagworte:
BLASTING
HEATING
LIGHTING
MECHANICAL ENGINEERING
POSITIVE DISPLACEMENT MACHINES FOR LIQUIDS
PUMPS
PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
WEAPONS
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creator NICKERSON MARK
KLEIN KENNETH
BENTE, III PAUL F
FOGELMAN KIMBER D
STAATS, III L. THOMPSON
BERGER TERRY A
description The invention is a device and method in a high-pressure chromatography system, such as a supercritical fluid chromatography (SFC) system, that uses a pump as a pressure source for precision pumping of a compressible fluid. The preferred exemplary embodiment comprises a pressure regulation assembly installed downstream from a compressible fluid pump but prior to combining the compressible flow with a relatively incompressible modifier flow stream. The present invention allows the replacement of an high-grade SFC pump in the compressible fluid flow stream with an inexpensive and imprecise pump. The imprecise pump becomes capable of moving the compressible fluid flow stream in a precise flow rate and pattern. The assembly dampens the damaging effects of an imprecise pump, such as large pressure oscillations caused by flow ripples and noisy pressure signals that do not meet precise SFC pumping requirements.
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subjects BLASTING
HEATING
LIGHTING
MECHANICAL ENGINEERING
POSITIVE DISPLACEMENT MACHINES FOR LIQUIDS
PUMPS
PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
WEAPONS
title Pump as a pressure source for supercritical fluid chromatography involving pressure regulators and a precision orifice
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