Cysteine protease inhibitors
This invention relates to derivatives of alpha-amino acid amides, to pharmaceutical compositions containing such compounds, and to their use in medicine as inhibitors of cysteine proteases, particularly the cathepsins. A compound of formula (I) is described or a pharmaceutically acceptable salt, hyd...
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| creator | REDDY ANDHE V. N THOMAS GEORGE SINGH RAJESHWAR KALETA JADWIGA DING QIZHU ZHOU NIAN MICETICH RONALD GEORGE WHITTAKER MARK |
| description | This invention relates to derivatives of alpha-amino acid amides, to pharmaceutical compositions containing such compounds, and to their use in medicine as inhibitors of cysteine proteases, particularly the cathepsins. A compound of formula (I) is described or a pharmaceutically acceptable salt, hydrate or solvate thereof. Pharmaceutically acceptable salts of the compounds of this invention include the sodium, potassium, magnesium, calcium, hydrogen chloride, tartaric acid, succinic acid, fumaric acid and p-toluenesulfonic acid salts. |
| format | Patent |
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N</au><au>THOMAS GEORGE</au><au>SINGH RAJESHWAR</au><au>KALETA JADWIGA</au><au>DING QIZHU</au><au>ZHOU NIAN</au><au>MICETICH RONALD GEORGE</au><au>WHITTAKER MARK</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Cysteine protease inhibitors</title><date>2003-10-21</date><risdate>2003</risdate><abstract>This invention relates to derivatives of alpha-amino acid amides, to pharmaceutical compositions containing such compounds, and to their use in medicine as inhibitors of cysteine proteases, particularly the cathepsins. A compound of formula (I) is described or a pharmaceutically acceptable salt, hydrate or solvate thereof. Pharmaceutically acceptable salts of the compounds of this invention include the sodium, potassium, magnesium, calcium, hydrogen chloride, tartaric acid, succinic acid, fumaric acid and p-toluenesulfonic acid salts.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Cysteine protease inhibitors |
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