Substituted 1-naphthoylguanidines, process for their preparation, their use as a medicament or diagnostic , and medicament containing them

Substituted 1-naphthoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them.Substituted 1-naphthoylguanidines of the formula Iin which R2 to R8 have the meanings indicated in the claims, are suitable as antiarrhythmic pharmaceuticals havi...

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Hauptverfasser: KLEEMAN HEINZ-WERNER, LANG HANS JOCHEN, ENGLERT HEINRICH CHRISTIAN, BRENDEL JOACHIM, GHATE ANIL VASANTRAO, ALBUS UDO, LAL BANSI
Format: Patent
Sprache:eng
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Zusammenfassung:Substituted 1-naphthoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them.Substituted 1-naphthoylguanidines of the formula Iin which R2 to R8 have the meanings indicated in the claims, are suitable as antiarrhythmic pharmaceuticals having a cardioprotective component for infarct prophylaxis and infarct treatment and for the treatment of angina pectoris. They also preventively inhibit the pathophysiological processes in the formation of ischemically induced damage, in particular in the production of ischemically induced cardiac arrhythmias.