Methods for modulation and inhibition of telomerase

It was found that normal human stem cells produce a regulated non-processive telomerase activity, while cancer cells produce a processive telomerase activity. Nucleotide analogs, such as 7-deaza-2'-deoxyquanosine-5'-triphosphate (7-deaza-dGTP) were found to be substrates for processive tel...

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Bibliographische Detailangaben

Hauptverfasser:	MAMIYA BLAIN, WINDLE BRADFORD E, FLETCHER TERACE M, MAINE IRA, SALAZAR MIQUEL, WAJIMA MAKOTO, CHEN SHIH-FONG, KERWIN SEAN M
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SUGARS
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