Pyrrolo[2,1-c][1,2,4] thiadiazoles and Pyrollo[2,1-c][1,12,4]oxadiazoles useful as nitric oxide synthase inhibitors

Pyrrolo[2,1-c][1,2,4]thiadiazole or pyrollo[2,1-c][1,2,4]oxadiazoles having the formula:or pharmaceutically acceptable salts thereof, useful as nitric oxide synthase inhibitors wherein each substituent is defined herein.

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Hauptverfasser: METZ SUZANNE, WEBBER R. KEITH, SNYDER JEFFERY S, MOORE WILLIAM M, PITZELE BARNETT S, HANSEN, JR. DONALD W, AWASTHI ALOK K, MOORMANN ALAN E, HALLINAN E. ANN, TOTH MIHALY V, SCHOLTEN JEFFREY A
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creator METZ SUZANNE
WEBBER R. KEITH
SNYDER JEFFERY S
MOORE WILLIAM M
PITZELE BARNETT S
HANSEN, JR. DONALD W
AWASTHI ALOK K
MOORMANN ALAN E
HALLINAN E. ANN
TOTH MIHALY V
SCHOLTEN JEFFREY A
description Pyrrolo[2,1-c][1,2,4]thiadiazole or pyrollo[2,1-c][1,2,4]oxadiazoles having the formula:or pharmaceutically acceptable salts thereof, useful as nitric oxide synthase inhibitors wherein each substituent is defined herein.
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subjects ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Pyrrolo[2,1-c][1,2,4] thiadiazoles and Pyrollo[2,1-c][1,12,4]oxadiazoles useful as nitric oxide synthase inhibitors
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