Aryl alkenamides derivatives as MCP-1 antagonists

Aryl alkenamides derivatives of Formula I or a pharmaceutically acceptable salt thereof are novel MCP-1 antagonists and are thus useful in the treatment of inflammation, atherosclerosis, restenosis, and immune disorders such as arthritis and transplant rejectionwhereV=O,S, NH or a bond;Ar can be uns...

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Hauptverfasser:	BOOTH RICHARD JOHN, CONNOR DAVID THOMAS, CARSON KENNETH GORDON, ROTH BRUCE DAVID, TRIVEDI BHARAT KALIDAS, GLYNN ROBERTA ELLEN, SCHWENDER CHARLES F, UNANGST PAUL CHARLES
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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