Aryl alkenamides derivatives as MCP-1 antagonists
Aryl alkenamides derivatives of Formula I or a pharmaceutically acceptable salt thereof are novel MCP-1 antagonists and are thus useful in the treatment of inflammation, atherosclerosis, restenosis, and immune disorders such as arthritis and transplant rejectionwhereV=O,S, NH or a bond;Ar can be uns...
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| creator | BOOTH RICHARD JOHN CONNOR DAVID THOMAS CARSON KENNETH GORDON ROTH BRUCE DAVID TRIVEDI BHARAT KALIDAS GLYNN ROBERTA ELLEN SCHWENDER CHARLES F UNANGST PAUL CHARLES |
| description | Aryl alkenamides derivatives of Formula I or a pharmaceutically acceptable salt thereof are novel MCP-1 antagonists and are thus useful in the treatment of inflammation, atherosclerosis, restenosis, and immune disorders such as arthritis and transplant rejectionwhereV=O,S, NH or a bond;Ar can be unsubstituted or substituted benzimidazole, phenyl, biphenyl, pyridyl, naphthyl, quinoline or isoquinoline. The other meanings for the terms are recited in the specification below. |
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The other meanings for the terms are recited in the specification below.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | Aryl alkenamides derivatives as MCP-1 antagonists |
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