Method for producing thiazolidinediones, and new thiazolidinediones

Improved process of compounds of formula IIIin whichA denotes CH=CH or SW denotes OX denotes S, O or NR2 in which the residue R2 is hydrogen or C1-C6 alkyl,Y denotes CH or NR denotes naphthyl, thienyl or phenyl which is optionally monosubstituted or disubstituted with C1-C3 alkyl, CF3, C1-C3 alkoxy,...

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Hauptverfasser: KUEHNLE HANS-FRIEDER, WITTE ERNSTRISTIAN, WOLFF HANS-PETER
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creator KUEHNLE HANS-FRIEDER
WITTE ERNSTRISTIAN
WOLFF HANS-PETER
description Improved process of compounds of formula IIIin whichA denotes CH=CH or SW denotes OX denotes S, O or NR2 in which the residue R2 is hydrogen or C1-C6 alkyl,Y denotes CH or NR denotes naphthyl, thienyl or phenyl which is optionally monosubstituted or disubstituted with C1-C3 alkyl, CF3, C1-C3 alkoxy, F, Cl or bromine,R1 denotes hydrogen or C1-C6 alkyl andn denotes 1-3by reducing a compound of the general formula IV,in which A, W, X, Y, R, R1 and n have the meanings stated abovewith activated aluminum in a protic solvent,as well as new compounds of formula III and pharmaceutical preparations containing these compounds.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Method for producing thiazolidinediones, and new thiazolidinediones
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