Phenyl amino squarate and thiadiazole dioxide beta-3 adrenergic receptor agonists

This invention provides compounds of Formula I having the structurewherein,R1, R2, and X are as defined hereinbefore, or a pharmaceutically acceptable salt thereof, which are useful in treating or inhibiting metabolic disorders related to insulin resistance or hyperglycemia (typically associated wit...

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Hauptverfasser: FREYMULLER JILL, FOBARE WILLIAM FLOYD
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creator FREYMULLER JILL
FOBARE WILLIAM FLOYD
description This invention provides compounds of Formula I having the structurewherein,R1, R2, and X are as defined hereinbefore, or a pharmaceutically acceptable salt thereof, which are useful in treating or inhibiting metabolic disorders related to insulin resistance or hyperglycemia (typically associated with obesity or glucose intolerance), atherosclerosis, gastrointestinal disorders, neurogenetic inflammation, glaucoma, ocular hypertension and frequent urination; and are particularly useful in the treatment or inhibition of type II diabetes.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Phenyl amino squarate and thiadiazole dioxide beta-3 adrenergic receptor agonists
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