Inhibitors of microsomal triglyceride transfer protein and method

Compounds are provided which inhibit microsomal triglyceride transfer protein and thus are useful for lowering serum lipids and treating atherosclerosis and related diseases. The compounds have the structure wherein R1 to R7, Q, X and Y are as defined herein.

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Bibliographische Detailangaben
Hauptverfasser:	POSS, MICHAEL A, SULSKY, RICHARD B, LAWRENCE, R. MICHAEL, MAGNIN, DAVID R, TINO, JOSEPH A, DICKSON, JOHN K, HOLAVA, HENRY M, PARTYKA, RICHARD A, BILLER, SCOTT A, LAWSON, JOHN E
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Compounds are provided which inhibit microsomal triglyceride transfer protein and thus are useful for lowering serum lipids and treating atherosclerosis and related diseases. The compounds have the structure wherein R1 to R7, Q, X and Y are as defined herein.