Electrophilic peptide analogs as inhibitors of trypsin-like enzymes

This invention relates to electrophilic dipeptide analogs conjugated to an N,N-disubstituted alpha -amino acid as inhibitors of trypsin-like serine protease enzymes.

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Bibliographische Detailangaben
Hauptverfasser:	AMPARO, EUGENE CRUZ, CACCIOLA, JOSEPH, WEBER, PATRICIA CAROL, ABELMAN, MATTHEW MARK, GALEMMO, JR., ROBERT ANTHONY, PACOFSKY, GREGORY JAMES, FEVIG, JOHN MATTHEW, KNABB, ROBERT MADARA, MILLER, WILLIAM HENRY
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	This invention relates to electrophilic dipeptide analogs conjugated to an N,N-disubstituted alpha -amino acid as inhibitors of trypsin-like serine protease enzymes.