Synthetic modification of Spinosyn compounds

The compounds of the present invention are prepared directly or indirectly by modifying the compounds that are naturally produced from Saccharopolyspora spinosa. The compounds of the invention have been shown to have activity against insects and mites. The compounds are prepared by modifying the rha...

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Hauptverfasser: ANZEVENO, PETER BIAGIO, THOREEN, BRIAN R, WORDEN, THOMAS V, SPARKS, THOMAS C, SCHOONOVER, JR., JOE RAYMOND, MARTYNOW, JACEK G, CREEMER, LAWRENCE CAMILLO, HEGDE, VIDYADHAR B, KIRST, HERBERT A, GIFFORD, JAMES MICHAEL, RICKS, MICHAEL J, HATTON, CHRISTOPHER J, MCLAREN, KEVIN L, GREEN, III, FREDERICK RICHARD, CROUSE, GARY D, DEAMICIS, CARL VINCENT
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creator ANZEVENO
PETER BIAGIO
THOREEN
BRIAN R
WORDEN
THOMAS V
SPARKS
THOMAS C
SCHOONOVER, JR.
JOE RAYMOND
MARTYNOW
JACEK G
CREEMER
LAWRENCE CAMILLO
HEGDE
VIDYADHAR B
KIRST
HERBERT A
GIFFORD
JAMES MICHAEL
RICKS
MICHAEL J
HATTON
CHRISTOPHER J
MCLAREN
KEVIN L
GREEN, III
FREDERICK RICHARD
CROUSE
GARY D
DEAMICIS
CARL VINCENT
description The compounds of the present invention are prepared directly or indirectly by modifying the compounds that are naturally produced from Saccharopolyspora spinosa. The compounds of the invention have been shown to have activity against insects and mites. The compounds are prepared by modifying the rhamnose sugar, modification of the forosamine sugar, or starting with pseuodoaglycone and then replacement with a nonsugar derivative or different sugar, modification of the 5,6,5-tricyclic and 12-membered macrocyclic lactone part of the compounds naturally produced or of the pseudoaglycone of the natural compounds.
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The compounds of the invention have been shown to have activity against insects and mites. The compounds are prepared by modifying the rhamnose sugar, modification of the forosamine sugar, or starting with pseuodoaglycone and then replacement with a nonsugar derivative or different sugar, modification of the 5,6,5-tricyclic and 12-membered macrocyclic lactone part of the compounds naturally produced or of the pseudoaglycone of the natural compounds.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record>
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recordid cdi_epo_espacenet_US6001981A
source esp@cenet
subjects CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
title Synthetic modification of Spinosyn compounds
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