Purification of hemoglobin

The present invention generally relates to methods for purifying hemoglobin solutions and to hemoglobin solutions obtained by the methods. In one aspect, such methods include removing contaminants in crude hemoglobin-containing lysates with heat treatment. In a further aspect, the present invention...

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Hauptverfasser: PLOMER, J. JEFFREY, RYLAND, JAMES R, TRAYLOR, DAVID W, MILNE, ERIN E, MATHEWS, ANTONY J, NEWAY, JUSTINIAN O, MATTHEWS, MAURA-ANN H, DURFEE, STEVEN L
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creator PLOMER
J. JEFFREY
RYLAND
JAMES R
TRAYLOR
DAVID W
MILNE
ERIN E
MATHEWS
ANTONY J
NEWAY
JUSTINIAN O
MATTHEWS
MAURA-ANN H
DURFEE
STEVEN L
description The present invention generally relates to methods for purifying hemoglobin solutions and to hemoglobin solutions obtained by the methods. In one aspect, such methods include removing contaminants in crude hemoglobin-containing lysates with heat treatment. In a further aspect, the present invention provides methods for producing substantially purified hemoglobin solutions using immobilized metal affinity chromatography, optionally following by anion exchange chromatography.
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JEFFREY ; RYLAND; JAMES R ; TRAYLOR; DAVID W ; MILNE; ERIN E ; MATHEWS; ANTONY J ; NEWAY; JUSTINIAN O ; MATTHEWS; MAURA-ANN H ; DURFEE; STEVEN L</creatorcontrib><description>The present invention generally relates to methods for purifying hemoglobin solutions and to hemoglobin solutions obtained by the methods. In one aspect, such methods include removing contaminants in crude hemoglobin-containing lysates with heat treatment. 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JEFFREY</au><au>RYLAND; JAMES R</au><au>TRAYLOR; DAVID W</au><au>MILNE; ERIN E</au><au>MATHEWS; ANTONY J</au><au>NEWAY; JUSTINIAN O</au><au>MATTHEWS; MAURA-ANN H</au><au>DURFEE; STEVEN L</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Purification of hemoglobin</title><date>1998-11-24</date><risdate>1998</risdate><abstract>The present invention generally relates to methods for purifying hemoglobin solutions and to hemoglobin solutions obtained by the methods. In one aspect, such methods include removing contaminants in crude hemoglobin-containing lysates with heat treatment. In a further aspect, the present invention provides methods for producing substantially purified hemoglobin solutions using immobilized metal affinity chromatography, optionally following by anion exchange chromatography.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record>
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subjects CHEMISTRY
GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC
GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE
title Purification of hemoglobin
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