Glucose responsive insulin secreting beta -cell lines and method for producing same

A line of beta cells is described which is capable of maintaining high levels of insulin secretion in culture. Such cells are useful in the treatment of diabetes, for example, by encapsulation of the cells in an insulin-permeable membrane device, followed by implantation into a diabetes patient.

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Bibliographische Detailangaben
Hauptverfasser: FIORE, DEBORAH M, KNAACK, DAVID, HEGRE, ORION D, LAURANCE, MEGAN E
Format: Patent
Sprache:eng
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Zusammenfassung:A line of beta cells is described which is capable of maintaining high levels of insulin secretion in culture. Such cells are useful in the treatment of diabetes, for example, by encapsulation of the cells in an insulin-permeable membrane device, followed by implantation into a diabetes patient.