Tumor targeting with polymeric molecules having extended conformation

Enhanced drug delivery to tumor tissue is obtained by attaching drug molecules to elongated polypeptide carrier molecules several orders of magnitude longer than wide. These are chosen to have a high net negative charge. The carrier molecules are created by unfolding long polypeptides by a large deg...

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Hauptverfasser: UZGIRIS, EGIDIJUS EDWARD
Format: Patent
Sprache:eng
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