Aromatic heterocyclic derivatives as enzyme inhibitors
The present invention discloses peptide aldehydes which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal t...
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| creator | TAMURA SUSAN YOSHIKO GE YU CARPENTER STEPHEN H BRUNCK TERENCE K RIPKA WILLIAM CHARLES SEMPLE JOSEPH EDWARD ARDECKY ROBERT JOHN |
| description | The present invention discloses peptide aldehydes which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal thrombosis. |
| format | Patent |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | Aromatic heterocyclic derivatives as enzyme inhibitors |
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