Inhibitors of protein farnesyltransferase and squalene synthase

The present invention provides a compound of the formula or a pharmaceutically acceptable salt thereof, which are useful in inhibiting protein farnesyltransferase and the farnesylation of the oncogene protein Ras or inhibiting de novo squalene production resulting in the inhibition of cholesterol bi...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	BAKER, WILLIAM R, FUNG, ANTHONY K. L, MCCLELLAN, WILLIAM J, PRASAD, RAJNANDAN, DONNER, B. GREGORY, O'CONNOR, STEPHEN J, GARVEY, DAVID S, ROCKWAY, TODD W, ROSENBERG, SAUL H, STEIN, HERMAN H, SHEN, WANG, SULLIVAN, GERARD M, FAKHOURY, STEPHEN A
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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