Processes and devices for continuously monitoring levels of analyte
In a process and devices or continuously measuring the concentration of an analyte in tissue. The tissue is provided with a hollow fiber having a pore size between the size of the analyte and the size of macromolecules, hollow fiber is perfused with a solution compatible with the tissue, and that so...
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| creator | SCHMIDT FRANSISCUS J SCHOONEN ADELBERT J. M WIENTJES KLAAS-JAN C |
| description | In a process and devices or continuously measuring the concentration of an analyte in tissue. The tissue is provided with a hollow fiber having a pore size between the size of the analyte and the size of macromolecules, hollow fiber is perfused with a solution compatible with the tissue, and that solution is supplied from the hollow fiber through a reactor for the analyte. The reactor has a second hollow fiber having a pore size between the size of the analyte and the size of macromolecules, and the second hollow fiber is located in a container which contains macromolecular reactants for detecting the analyte and a signal producing system coupled therewith. The perfusion fluid is fed from the reactor to an eliminator for the analyte, whereby at least 95% of the remaining analyte is removed from the perfusion fluid and the perfusion fluid is reintroduced into said first hollow fiber. The process and devices operate as a closed circuit and therefore this method can be continued over a longer period of time than known methods, without the need to replace reservoirs. |
| format | Patent |
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The process and devices operate as a closed circuit and therefore this method can be continued over a longer period of time than known methods, without the need to replace reservoirs.</description><edition>6</edition><language>eng</language><subject>DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY ; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR ; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY ; DIAGNOSIS ; HUMAN NECESSITIES ; HYGIENE ; IDENTIFICATION ; MEDICAL OR VETERINARY SCIENCE ; SURGERY</subject><creationdate>1997</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19970401&DB=EPODOC&CC=US&NR=5615671A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19970401&DB=EPODOC&CC=US&NR=5615671A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SCHMIDT; FRANSISCUS J</creatorcontrib><creatorcontrib>SCHOONEN; ADELBERT J. 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The perfusion fluid is fed from the reactor to an eliminator for the analyte, whereby at least 95% of the remaining analyte is removed from the perfusion fluid and the perfusion fluid is reintroduced into said first hollow fiber. 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M</creatorcontrib><creatorcontrib>WIENTJES; KLAAS-JAN C</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SCHMIDT; FRANSISCUS J</au><au>SCHOONEN; ADELBERT J. M</au><au>WIENTJES; KLAAS-JAN C</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Processes and devices for continuously monitoring levels of analyte</title><date>1997-04-01</date><risdate>1997</risdate><abstract>In a process and devices or continuously measuring the concentration of an analyte in tissue. The tissue is provided with a hollow fiber having a pore size between the size of the analyte and the size of macromolecules, hollow fiber is perfused with a solution compatible with the tissue, and that solution is supplied from the hollow fiber through a reactor for the analyte. The reactor has a second hollow fiber having a pore size between the size of the analyte and the size of macromolecules, and the second hollow fiber is located in a container which contains macromolecular reactants for detecting the analyte and a signal producing system coupled therewith. The perfusion fluid is fed from the reactor to an eliminator for the analyte, whereby at least 95% of the remaining analyte is removed from the perfusion fluid and the perfusion fluid is reintroduced into said first hollow fiber. The process and devices operate as a closed circuit and therefore this method can be continued over a longer period of time than known methods, without the need to replace reservoirs.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY DIAGNOSIS HUMAN NECESSITIES HYGIENE IDENTIFICATION MEDICAL OR VETERINARY SCIENCE SURGERY |
| title | Processes and devices for continuously monitoring levels of analyte |
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