Method for preparation of a shaped chitin body containing a physiologically active substance

A shaped chitin body containing a high content of a physiologically active substance, such as a drug to be used for the cure or prevention of disease, is prepared by incorporating said physiologically active substance into a dope comprising (a) a water-insoluble chitin, (b) lithium chloride, and (c)...

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Hauptverfasser: MOTOSUGI, KENZO, KIFUNE, KOJI, TANAE, HIROYUKI
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creator MOTOSUGI
KENZO
KIFUNE
KOJI
TANAE
HIROYUKI
description A shaped chitin body containing a high content of a physiologically active substance, such as a drug to be used for the cure or prevention of disease, is prepared by incorporating said physiologically active substance into a dope comprising (a) a water-insoluble chitin, (b) lithium chloride, and (c) N-methylpyrrolidone and/or dimethylacetamide, with the amount of said physiologically active substance incorporated being 0.5 wt. % or more with respect to the amount of the chitin contained in said dope, and thereafter coagulating the resulting mixture with a coagulant to obtain a shaped body. The high content of the physiologically active substance thus incorporated in the shaped chitin can be slowly released therefrom over a long period of time. The shaped-chitin of the present invention is characterized by long duration of the physiological activity of the active substance contained therein.
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subjects AGRICULTURE
ANIMAL HUSBANDRY
BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES
CHEMISTRY
COMPOSITIONS BASED THEREON
COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC MACROMOLECULAR COMPOUNDS
PEST REPELLANTS OR ATTRACTANTS
PLANT GROWTH REGULATORS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF
THEIR PREPARATION OR CHEMICAL WORKING-UP
TRAPPING
title Method for preparation of a shaped chitin body containing a physiologically active substance
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