Trehalose derivatives

A trehalose derivative of the formula: wherein one, two, three or four of R , R , R , R , R , R , R and R are independently selected from the group consisting of C1-40 aliphatic acyl groups and all the rest of them are hydrogen atoms, with the proviso that: a) when one of them is C1-40 aliphatic acy...

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Hauptverfasser: KATO, YOSHIKO, SHOGAKI, TAKESHI, YOSHINAGA, JUNJI, KAKITA, TAKAO, OZEKI, HIROMI
Format: Patent
Sprache:eng
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Zusammenfassung:A trehalose derivative of the formula: wherein one, two, three or four of R , R , R , R , R , R , R and R are independently selected from the group consisting of C1-40 aliphatic acyl groups and all the rest of them are hydrogen atoms, with the proviso that: a) when one of them is C1-40 aliphatic acyl group, then it is not 2-palmitoyl or 6-aliphatic acyl, b) when two of them are C1-40 aliphatic acyl groups, then they are not located at corresponding positions with each other, c) when three of them are C1-40 aliphatic acyl groups, then they are not 2,3,2 min -tripalmitoyl, and d) when four of them are C1-40 aliphatic acyl groups, then they are not located at corresponding positions with each other or at 2,3,4,2 min - or 2,3,6,2 min -positions. The compounds of the above formula have anti-tumor activity.