Inhibition of bone loss by 4-substituted-5-hydroxy-2(5H)-furanones

This invention relates to 4-substituted-5-hydroxy-2(5H)-furanones, to the process for their preparation, to pharmaceutical compositions containing said 4-substituted-5-hydroxy-2(5H)-furanones and to the use of said 4-substituted-5-hydroxy-2(5H)-furanones for modifying the balance between bone produc...

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Hauptverfasser: SABATUCCI, JOSEPH P, LEFEBVRE, YVON, HAYWARD, MARSHALL A, JIRKOVSKY, IVO L
Format: Patent
Sprache:eng
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Zusammenfassung:This invention relates to 4-substituted-5-hydroxy-2(5H)-furanones, to the process for their preparation, to pharmaceutical compositions containing said 4-substituted-5-hydroxy-2(5H)-furanones and to the use of said 4-substituted-5-hydroxy-2(5H)-furanones for modifying the balance between bone production and bone resorption in a host animal, including man.