Immunoconjugates joined by thioether bonds having reduced toxicity and improved selectivity

Method for producing an immunoconjugate comprising the steps of reacting a toxin or protein with a heterobifunctional reagent having the following general formula: where R1 is: -(CH2)n- or where n = 1 to 10; and where R2 is selected from the group consisting of o- and p-nitrophenyl, 2-chloro-4-nitro...

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Hauptverfasser:	SIVAM, GOWSALA
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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