Anthracycline derivatives having cytostatic activity
The invention relates to new anthracycline derivatives having cytostatic activity and the general formula I I in which the radicals R1 is hydrogen or a hydroxyl group, R2 is hydrogen or a hydroxyl group or a structure of the formula II, and R3 is a hydroxyl group or a structure of the formula II II...
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| creator | BERSCHEID HANS G KOLAR CENEK KRAEMER HANS P HOFFMANN DIETER BOETTGER DIRK HERMENTIN PETER PAAL MICHAEL |
| description | The invention relates to new anthracycline derivatives having cytostatic activity and the general formula I I in which the radicals R1 is hydrogen or a hydroxyl group, R2 is hydrogen or a hydroxyl group or a structure of the formula II, and R3 is a hydroxyl group or a structure of the formula II II in which R4 is an aliphatic or aromatic acyl group, with the proviso that at least one of the radicals R2 and R3 has a structure of the formula II, which are optionally in the form of a salt of an inorganic or organic acid, as well as to the process for the preparation thereof, and to the use thereof in pharmaceuticals. |
| format | Patent |
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HANS G</creatorcontrib><creatorcontrib>KOLAR; CENEK</creatorcontrib><creatorcontrib>KRAEMER; HANS P</creatorcontrib><creatorcontrib>HOFFMANN; DIETER</creatorcontrib><creatorcontrib>BOETTGER; DIRK</creatorcontrib><creatorcontrib>HERMENTIN; PETER</creatorcontrib><creatorcontrib>PAAL; MICHAEL</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BERSCHEID; HANS G</au><au>KOLAR; CENEK</au><au>KRAEMER; HANS P</au><au>HOFFMANN; DIETER</au><au>BOETTGER; DIRK</au><au>HERMENTIN; PETER</au><au>PAAL; MICHAEL</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Anthracycline derivatives having cytostatic activity</title><date>1990-04-03</date><risdate>1990</risdate><abstract>The invention relates to new anthracycline derivatives having cytostatic activity and the general formula I I in which the radicals R1 is hydrogen or a hydroxyl group, R2 is hydrogen or a hydroxyl group or a structure of the formula II, and R3 is a hydroxyl group or a structure of the formula II II in which R4 is an aliphatic or aromatic acyl group, with the proviso that at least one of the radicals R2 and R3 has a structure of the formula II, which are optionally in the form of a salt of an inorganic or organic acid, as well as to the process for the preparation thereof, and to the use thereof in pharmaceuticals.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS |
| title | Anthracycline derivatives having cytostatic activity |
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