Steroid cream formulation

Steroid cream formulation

A steroid cream formulation which has enhanced physical and chemical stability is formed of (11 beta ,17 alpha )-17-(ethylthio)-9 alpha -fluoro-11 beta -hydroxy-17-(methylthio)androsta-1,4-dien-3-one (tipredane), and a vehicle containing as major ingredients propylene glycol and water together with...

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Hauptverfasser: PAYNE, NICHOLAS I, TIMMINS, PETER
Format: Patent
Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator PAYNE
NICHOLAS I
TIMMINS
PETER
description A steroid cream formulation which has enhanced physical and chemical stability is formed of (11 beta ,17 alpha )-17-(ethylthio)-9 alpha -fluoro-11 beta -hydroxy-17-(methylthio)androsta-1,4-dien-3-one (tipredane), and a vehicle containing as major ingredients propylene glycol and water together with a sodium citrate or potassium citrate buffer to impart an acid value to the cream formulation of greater than 3, a high melting point wax, such as white wax, to impart proper consistency without adversely affecting stability of the tipredane, benzyl alcohol as a preservative, together with one or more emulsifiers, which include glyceryl stearate, one or more emollients which include isopropyl isostearate or isopropyl palmitate, lubricants and other conventional cream formulation ingredients.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Steroid cream formulation
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