Benoz-fused cycloalkane trans-1,2-diamine derivatives

Benzo-fused cycloalkane and oxa- and thiacycloalkane trans-1,2-diamine compounds of the formula: wherein A, B, C, D, n, X, Y, R, R , R and R are as defined in the specification, e.g., trans-3,4-dichloro-N-methyl-N-[2-(pyrrolidin-1-yl)-5-methoxy 1,2,3,4-tetrahydronaphth-1-yl]benzeneacetamide, and the...

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Hauptverfasser: RAJAGOPALAN, PARTHASARATHI, PENNEV, PENIO, SCRIBNER, RICHARD M
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creator RAJAGOPALAN
PARTHASARATHI
PENNEV
PENIO
SCRIBNER
RICHARD M
description Benzo-fused cycloalkane and oxa- and thiacycloalkane trans-1,2-diamine compounds of the formula: wherein A, B, C, D, n, X, Y, R, R , R and R are as defined in the specification, e.g., trans-3,4-dichloro-N-methyl-N-[2-(pyrrolidin-1-yl)-5-methoxy 1,2,3,4-tetrahydronaphth-1-yl]benzeneacetamide, and the pharmaceutically acceptable salts or N-oxides thereof, are useful as analgesics and/or diuretics.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Benoz-fused cycloalkane trans-1,2-diamine derivatives
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