Process for the preparation of 7-amino-3-(3-formamidopyridinium)methyl-3-cephem-4-carboxylate, and its use for the synthesis of beta -lactam antibiotics

7-Amino-3-(3-formamidopyridinium)methyl-3-cephem-4-carboxylate of the formula is produced by (a) reacting a compound of the formula in which R3 is a phenacetyl or a thienylacetyl group, with 3-formamidopyridine to give the compound of the formula and (b) splitting off the R3 radical. The product can...

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Hauptverfasser:	ANGERBAUER, ROLF
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	ANGERBAUER ROLF
description	7-Amino-3-(3-formamidopyridinium)methyl-3-cephem-4-carboxylate of the formula is produced by (a) reacting a compound of the formula in which R3 is a phenacetyl or a thienylacetyl group, with 3-formamidopyridine to give the compound of the formula and (b) splitting off the R3 radical. The product can then be coupled to a suitable acid to produce a cephalosporin and the formyl radical may be split off.
format	Patent
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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	Process for the preparation of 7-amino-3-(3-formamidopyridinium)methyl-3-cephem-4-carboxylate, and its use for the synthesis of beta -lactam antibiotics
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