Chemical process

There is described a method for synthesizing 3-nitro-1,2-cyclopentanedione salts which are substituted in the 4-position with an alkyl substituent and in the 5-position with an electron withdrawing substituent. The method comprises the addition and spontaneous cyclization reaction of a nitro olefin...

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Bibliographische Detailangaben
Hauptverfasser: WHITTEN, CHARLES E
Format: Patent
Sprache:eng
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Zusammenfassung:There is described a method for synthesizing 3-nitro-1,2-cyclopentanedione salts which are substituted in the 4-position with an alkyl substituent and in the 5-position with an electron withdrawing substituent. The method comprises the addition and spontaneous cyclization reaction of a nitro olefin with a pyruvate anion. The salts can be converted to the nitro diones or used as intermediates in the preparation of amino reductones.