11 alpha -Amino-androstanes
(I) wherein R1 is a C1-8 alkyl group or a C3-7 cycloalkyl group; R2 is a hydrogen atom, a C1-6 alkoxy group or a C2-5 alkanoyloxy group; R3 is a C1-6 alkyl group or a C3-7 cycloalkyl group; and R4 is a group -OR5 or -OCOR6 where R5 is an optionally substituted alkyl or alkenyl group which may contai...
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| creator | PHILLIPPS GORDON H EWAN GEORGE B HUMBER DAVID C COOMBER BARRY A |
| description | (I) wherein R1 is a C1-8 alkyl group or a C3-7 cycloalkyl group; R2 is a hydrogen atom, a C1-6 alkoxy group or a C2-5 alkanoyloxy group; R3 is a C1-6 alkyl group or a C3-7 cycloalkyl group; and R4 is a group -OR5 or -OCOR6 where R5 is an optionally substituted alkyl or alkenyl group which may contain up to 6 carbon atoms, an optionally substituted C3-7 cycloalkyl group, a phenyl group or a carbon-attached 5-7 membered heterocyclic ring in which the hetero-atom is selected from nitrogen, oxygen and sulphur, and R6 is a hydrogen atom or a group R5 as defined above; provided that when the compounds contain a 5 beta -hydrogen atom, R2 is a hydrogen atom and salts thereof, which compounds have activity as antidysthythmic agents. |
| format | Patent |
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and R4 is a group -OR5 or -OCOR6 where R5 is an optionally substituted alkyl or alkenyl group which may contain up to 6 carbon atoms, an optionally substituted C3-7 cycloalkyl group, a phenyl group or a carbon-attached 5-7 membered heterocyclic ring in which the hetero-atom is selected from nitrogen, oxygen and sulphur, and R6 is a hydrogen atom or a group R5 as defined above; provided that when the compounds contain a 5 beta -hydrogen atom, R2 is a hydrogen atom and salts thereof, which compounds have activity as antidysthythmic agents.</description><edition>3</edition><language>eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; STEROIDS</subject><creationdate>1985</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19850507&DB=EPODOC&CC=US&NR=4515786A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19850507&DB=EPODOC&CC=US&NR=4515786A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PHILLIPPS; 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GORDON H</creator><creator>EWAN; GEORGE B</creator><creator>HUMBER; DAVID C</creator><creator>COOMBER; BARRY A</creator><scope>EVB</scope></search><sort><creationdate>19850507</creationdate><title>11 alpha -Amino-androstanes</title><author>PHILLIPPS; GORDON H ; EWAN; GEORGE B ; HUMBER; DAVID C ; COOMBER; BARRY A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US4515786A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1985</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>STEROIDS</topic><toplevel>online_resources</toplevel><creatorcontrib>PHILLIPPS; GORDON H</creatorcontrib><creatorcontrib>EWAN; GEORGE B</creatorcontrib><creatorcontrib>HUMBER; DAVID C</creatorcontrib><creatorcontrib>COOMBER; BARRY A</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PHILLIPPS; GORDON H</au><au>EWAN; GEORGE B</au><au>HUMBER; DAVID C</au><au>COOMBER; BARRY A</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>11 alpha -Amino-androstanes</title><date>1985-05-07</date><risdate>1985</risdate><abstract>(I) wherein R1 is a C1-8 alkyl group or a C3-7 cycloalkyl group; R2 is a hydrogen atom, a C1-6 alkoxy group or a C2-5 alkanoyloxy group; R3 is a C1-6 alkyl group or a C3-7 cycloalkyl group; and R4 is a group -OR5 or -OCOR6 where R5 is an optionally substituted alkyl or alkenyl group which may contain up to 6 carbon atoms, an optionally substituted C3-7 cycloalkyl group, a phenyl group or a carbon-attached 5-7 membered heterocyclic ring in which the hetero-atom is selected from nitrogen, oxygen and sulphur, and R6 is a hydrogen atom or a group R5 as defined above; provided that when the compounds contain a 5 beta -hydrogen atom, R2 is a hydrogen atom and salts thereof, which compounds have activity as antidysthythmic agents.</abstract><edition>3</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS STEROIDS |
| title | 11 alpha -Amino-androstanes |
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