Theophyllinylmethyldioxolane derivatives, methods for their preparation and pharmaceutical compositions containing them

Compounds of the following general formula I wherein: X and Y are different from each other and represent -CH2- or an oxygen atom; R represents a radical selected from hydroxy, bromo, acetoxy, pyrrolidino, morpholino, piperazino and piperazino substituted at the position 4 by a carbethoxy, benzyl, p...

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Hauptverfasser: SPINELLI, SILVANO, CHIODONI, UGO, FRANZONE, JOSE S
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creator SPINELLI
SILVANO
CHIODONI
UGO
FRANZONE
JOSE S
description Compounds of the following general formula I wherein: X and Y are different from each other and represent -CH2- or an oxygen atom; R represents a radical selected from hydroxy, bromo, acetoxy, pyrrolidino, morpholino, piperazino and piperazino substituted at the position 4 by a carbethoxy, benzyl, phenyl, halophenyl, methoxyphenyl or trifluoromethylphenyl group, or when X is -CH2- and Y is an oxygen atom, R may represent also chloro; methods for their preparation; pharmaceutical compositions containing them. The compounds possess a remarkable antitussive activity.
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subjects CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
THEIR RELEVANT APPARATUS
TRANSPORTING
title Theophyllinylmethyldioxolane derivatives, methods for their preparation and pharmaceutical compositions containing them
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