Method for treating a picorna virus infection

A method of treating picorna viral infections, particularly of the picornaviruses, is provided which comprises treating the patient with an effective amount of a compound of the formula wherein R is hydrogen or methyl; and R' is lower alkyl, allyl, beta -hydroxyethyl, beta -aminoethyl, omega -a...

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Hauptverfasser: VASSILEVA, RAGKA TANEVA, GALABOV, ANGEL SIMEONOV, VELICHKOVA, EMILIA HRISTOVA, SHINDAROV, LUBOMIR MIHAYLOV, STOYCHEVA, DUSHKA STANEVA, VASSILEV, GEORGI NIKOLOV, DIMCHEVA, ZLATKA PETKOVA
Format: Patent
Sprache:eng
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Zusammenfassung:A method of treating picorna viral infections, particularly of the picornaviruses, is provided which comprises treating the patient with an effective amount of a compound of the formula wherein R is hydrogen or methyl; and R' is lower alkyl, allyl, beta -hydroxyethyl, beta -aminoethyl, omega -aminohexyl, a fatty acid radical, methoxyphenyl, chlorophenyl, phenyl, benzyl, tolyl, hydroxyphenyl, carboxyphenyl, chinoyl, carboxyhydroxyphenyl, hydroxynitrophenyl, nitrophenyl, hydroxychlorophenyl, chloronitrophenyl, phenylthioureidohexyl, trimethylphenyl, methylchlorophenyl, pyridyl, acetylphenyl, acetylaminophenyl, dimethylaminophenyl, aminopyridyl, phenylthioureidopyridyl, phenylthioureidonaphtyl, aminonaphthyl, chlorophenylthioureidophenyl, furfuryl, dichlorophenyl or allylthioureidophenyl. The compound may be administered orally, preferably in dosages of from 40 to 200 mg per kilogram body weight.