ISOLATION AND PURIFICATION OF ACTIVE PRINCIPLE OF FRUIT OF SYNSEPALUM DULCIFICUM

A process for the purification of the active principle of the fruit of the plant Synsepalum dulcificum is disclosed. The process includes contacting the fruit with a suspension of polyvinyl pyrrolidone, followed by adsorption of the active principle by means of chromatography procedures. By followin...

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Bibliographische Detailangaben
Hauptverfasser: GIROUX, EUGENE L, HENKIN, ROBERT I
Format: Patent
Sprache:eng
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Zusammenfassung:A process for the purification of the active principle of the fruit of the plant Synsepalum dulcificum is disclosed. The process includes contacting the fruit with a suspension of polyvinyl pyrrolidone, followed by adsorption of the active principle by means of chromatography procedures. By following the process in accordance with the present invention, proteases and tannins are substantially completely eliminated from the final product. The active principle of this fruit, when prepared in accordance with the present invention, has been found to be particularly useful in controlling obesity in human beings.