Aminophenylamidines, their production and their medicinal use

4-Amino substituted phenylamidine are anthelmintics. The compounds, of which N-(4-aminophenyl)-N',N'-dimethylacetamidine is a representative embodiment, can be prepared through treatment of a 4-amino aniline with a carboxylic acidamide or thioamide, reduction of an appropriately substitute...

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Hauptverfasser:	FLUCKE, WINFRIED, WOLLWEBER, HARTMUND
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator	FLUCKE WINFRIED WOLLWEBER HARTMUND
description	4-Amino substituted phenylamidine are anthelmintics. The compounds, of which N-(4-aminophenyl)-N',N'-dimethylacetamidine is a representative embodiment, can be prepared through treatment of a 4-amino aniline with a carboxylic acidamide or thioamide, reduction of an appropriately substituted 4-aminophenyl-amidine, optionally followed by alkylation of the resultant 4-aminophenyl-amidine, formation of a Schiff base followed by quaternization and hydrolysis, or hydrolysis of a 4-acylaminophenylamidine.
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The compounds, of which N-(4-aminophenyl)-N',N'-dimethylacetamidine is a representative embodiment, can be prepared through treatment of a 4-amino aniline with a carboxylic acidamide or thioamide, reduction of an appropriately substituted 4-aminophenyl-amidine, optionally followed by alkylation of the resultant 4-aminophenyl-amidine, formation of a Schiff base followed by quaternization and hydrolysis, or hydrolysis of a 4-acylaminophenylamidine.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1975</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLB1zM3Myy_ISM2rzEnMzUzJzEst1lEoyUjNLFIoKMpPKU0uyczPU0jMS4EK5qamZCZn5iXmKJQWp_IwsKYl5hSn8kJpbgZ5N9cQZw_d1IL8-NTigsTk1LzUkvjQYGNLI1MTcwNHY8IqAJ4YL-k</recordid><startdate>19751209</startdate><enddate>19751209</enddate><creator>FLUCKE; WINFRIED</creator><creator>WOLLWEBER; HARTMUND</creator><scope>EVB</scope></search><sort><creationdate>19751209</creationdate><title>Aminophenylamidines, their production and their medicinal use</title><author>FLUCKE; WINFRIED ; WOLLWEBER; HARTMUND</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US3925470A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1975</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>FLUCKE; WINFRIED</creatorcontrib><creatorcontrib>WOLLWEBER; HARTMUND</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>FLUCKE; WINFRIED</au><au>WOLLWEBER; HARTMUND</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Aminophenylamidines, their production and their medicinal use</title><date>1975-12-09</date><risdate>1975</risdate><abstract>4-Amino substituted phenylamidine are anthelmintics. 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title	Aminophenylamidines, their production and their medicinal use
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