Method for the production of d(-)-{60 -aminobenzylpenicillin directly from natural penicillins

Method for the production of d(-)-{60 -aminobenzylpenicillin directly from natural penicillins

A method for preparing D(-)- alpha -amino-benzylpenicillin directly from natural penicillins by an one-stage process. The natural penicillins are esterified, transformed into iminochloride and then into iminoethers which is reacted simultaneously with water and chloride of phenylglycine hydrochlorid...

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Hauptverfasser: CIGNARELLA, GIORGIO, PASQUALUCCI, CARMINE RENATO, GIOVANNI, SESTO SAN, BONFANTI
Format: Patent
Sprache:eng
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator CIGNARELLA
GIORGIO
PASQUALUCCI
CARMINE RENATO
GIOVANNI
SESTO SAN
BONFANTI
GIOVANNI
description A method for preparing D(-)- alpha -amino-benzylpenicillin directly from natural penicillins by an one-stage process. The natural penicillins are esterified, transformed into iminochloride and then into iminoethers which is reacted simultaneously with water and chloride of phenylglycine hydrochloride to give the desired product.
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HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Method for the production of d(-)-{60 -aminobenzylpenicillin directly from natural penicillins
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