Synthesis and Biological Activity of Phosphoramidimidate and Phosphoramidate DNA

Oligonucleotides comprising phosphoramidimidate internucleotide linkages, and methods of efficiently synthesizing these oligonucleotides with high yield are provided. These oligonucleotides form duplexes with complementary DNA or RNA that are more stable than natural DNA or DNA/RNA complexes, are ac...

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Bibliographische Detailangaben

Hauptverfasser:	Alawneh, Ayman, Caruthers, Marvin
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY SUGARS
Online-Zugang:	Volltext bestellen
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