METHODS OF IMPLANTING ENGINEERED TISSUE CONSTRUCTS

The present disclosure provides engineered tissue constructs having a population of cells. such as hepatocytes and stromal cells. and methods of implanting the same (e.g., for treating a disease or disorder, such as acute liver failure, a urea cycle disorder, or hyperbilirubinemia (e.g., in a subjec...

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Bibliographische Detailangaben
Hauptverfasser: NORMAN, Timothy Alfred, WILSON, Christopher Garrison, CHHABRA, Arnav, LANDE-DINER, Laura, HAYWARD, Alison, JAMIEL, Morgan, GADE, Nikitha, MARTURANO, Joseph E, LA MURAGLIA, Glenn Michael, CHEN, Amanda, TAKIFF, Howard, LOWERY, Thomas Jay
Format: Patent
Sprache:eng
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Zusammenfassung:The present disclosure provides engineered tissue constructs having a population of cells. such as hepatocytes and stromal cells. and methods of implanting the same (e.g., for treating a disease or disorder, such as acute liver failure, a urea cycle disorder, or hyperbilirubinemia (e.g., in a subject having Crigler-Najjar syndrome) in a human subject in need thereof).