PROCESS FOR MANUFACTURING A MICROFLUIDIC DEVICE

A process for manufacturing a microfluidic device including:a) providing a first substrate having a first surface including a first flat part and a first concavity and a second substrate having a second surface including a second flat part and an optional second concavity,b) coating at least one of...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: ZUILHOF, Johannes Teunis, SCHERES, Luc, RIJO DA COSTA CARVALHO, Rui Pedro, KNOBEN, Wout
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator ZUILHOF, Johannes Teunis
SCHERES, Luc
RIJO DA COSTA CARVALHO, Rui Pedro
KNOBEN, Wout
description A process for manufacturing a microfluidic device including:a) providing a first substrate having a first surface including a first flat part and a first concavity and a second substrate having a second surface including a second flat part and an optional second concavity,b) coating at least one of the first surface and the second surface with a coating composition includingi) a monomer A including one moiety represented by CH2=CR1R2 wherein R1 represents H or CH3 and R2 represents -COO- or -CONH-, and a non-ionic hydrophilic moiety;ii) a monomer B including two or more moieties represented by CH2=CR1R2 wherein R1 represents H or CH3 and R2 represents -COO- or -CONH-, and a non-ionic hydrophilic moiety;iii) optionally a photoinitiator;iv) optionally a diluent;c) evaporating the diluent if present, and forming a liquid coating;d) contacting the substrates so as to obtain an assembly in which the first flat part and the second flat part contact each other to define a microfluidic structure between the first and the second surfaces, wherein the microfluidic structure includes the first concavity and the optional second concavity; ande) at least partially irradiating the assembly with light having a wavelength between 200 and 800 nm to crosslink the liquid coating to bond the first flat part and the second flat part and obtain a crosslinked coating on at least the first concavity.A microfluidic device having two parts bonded together with a crosslinked composition and a channel which includes at least partly the crosslinked composition as a coating.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US2024416638A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US2024416638A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US2024416638A13</originalsourceid><addsrcrecordid>eNrjZNAPCPJ3dg0OVnDzD1LwdfQLdXN0DgkN8vRzV3BU8PV0DvJ38wn1dPF0VnBxDfN0duVhYE1LzClO5YXS3AzKbq4hzh66qQX58anFBYnJqXmpJfGhwUYGRiYmhmZmxhaOhsbEqQIAowEm9w</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>PROCESS FOR MANUFACTURING A MICROFLUIDIC DEVICE</title><source>esp@cenet</source><creator>ZUILHOF, Johannes Teunis ; SCHERES, Luc ; RIJO DA COSTA CARVALHO, Rui Pedro ; KNOBEN, Wout</creator><creatorcontrib>ZUILHOF, Johannes Teunis ; SCHERES, Luc ; RIJO DA COSTA CARVALHO, Rui Pedro ; KNOBEN, Wout</creatorcontrib><description>A process for manufacturing a microfluidic device including:a) providing a first substrate having a first surface including a first flat part and a first concavity and a second substrate having a second surface including a second flat part and an optional second concavity,b) coating at least one of the first surface and the second surface with a coating composition includingi) a monomer A including one moiety represented by CH2=CR1R2 wherein R1 represents H or CH3 and R2 represents -COO- or -CONH-, and a non-ionic hydrophilic moiety;ii) a monomer B including two or more moieties represented by CH2=CR1R2 wherein R1 represents H or CH3 and R2 represents -COO- or -CONH-, and a non-ionic hydrophilic moiety;iii) optionally a photoinitiator;iv) optionally a diluent;c) evaporating the diluent if present, and forming a liquid coating;d) contacting the substrates so as to obtain an assembly in which the first flat part and the second flat part contact each other to define a microfluidic structure between the first and the second surfaces, wherein the microfluidic structure includes the first concavity and the optional second concavity; ande) at least partially irradiating the assembly with light having a wavelength between 200 and 800 nm to crosslink the liquid coating to bond the first flat part and the second flat part and obtain a crosslinked coating on at least the first concavity.A microfluidic device having two parts bonded together with a crosslinked composition and a channel which includes at least partly the crosslinked composition as a coating.</description><language>eng</language><subject>ADHESIVES ; CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE ; CHEMICAL PAINT OR INK REMOVERS ; CHEMISTRY ; COATING COMPOSITIONS, e.g. PAINTS, VARNISHES ORLACQUERS ; CORRECTING FLUIDS ; DYES ; FILLING PASTES ; INKS ; LAYERED PRODUCTS ; LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT ORNON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM ; METALLURGY ; MISCELLANEOUS APPLICATIONS OF MATERIALS ; MISCELLANEOUS COMPOSITIONS ; NATURAL RESINS ; PAINTS ; PASTES OR SOLIDS FOR COLOURING OR PRINTING ; PERFORMING OPERATIONS ; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL ; POLISHES ; TRANSPORTING ; USE OF MATERIALS THEREFOR ; WOODSTAINS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20241219&amp;DB=EPODOC&amp;CC=US&amp;NR=2024416638A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20241219&amp;DB=EPODOC&amp;CC=US&amp;NR=2024416638A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ZUILHOF, Johannes Teunis</creatorcontrib><creatorcontrib>SCHERES, Luc</creatorcontrib><creatorcontrib>RIJO DA COSTA CARVALHO, Rui Pedro</creatorcontrib><creatorcontrib>KNOBEN, Wout</creatorcontrib><title>PROCESS FOR MANUFACTURING A MICROFLUIDIC DEVICE</title><description>A process for manufacturing a microfluidic device including:a) providing a first substrate having a first surface including a first flat part and a first concavity and a second substrate having a second surface including a second flat part and an optional second concavity,b) coating at least one of the first surface and the second surface with a coating composition includingi) a monomer A including one moiety represented by CH2=CR1R2 wherein R1 represents H or CH3 and R2 represents -COO- or -CONH-, and a non-ionic hydrophilic moiety;ii) a monomer B including two or more moieties represented by CH2=CR1R2 wherein R1 represents H or CH3 and R2 represents -COO- or -CONH-, and a non-ionic hydrophilic moiety;iii) optionally a photoinitiator;iv) optionally a diluent;c) evaporating the diluent if present, and forming a liquid coating;d) contacting the substrates so as to obtain an assembly in which the first flat part and the second flat part contact each other to define a microfluidic structure between the first and the second surfaces, wherein the microfluidic structure includes the first concavity and the optional second concavity; ande) at least partially irradiating the assembly with light having a wavelength between 200 and 800 nm to crosslink the liquid coating to bond the first flat part and the second flat part and obtain a crosslinked coating on at least the first concavity.A microfluidic device having two parts bonded together with a crosslinked composition and a channel which includes at least partly the crosslinked composition as a coating.</description><subject>ADHESIVES</subject><subject>CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE</subject><subject>CHEMICAL PAINT OR INK REMOVERS</subject><subject>CHEMISTRY</subject><subject>COATING COMPOSITIONS, e.g. PAINTS, VARNISHES ORLACQUERS</subject><subject>CORRECTING FLUIDS</subject><subject>DYES</subject><subject>FILLING PASTES</subject><subject>INKS</subject><subject>LAYERED PRODUCTS</subject><subject>LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT ORNON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM</subject><subject>METALLURGY</subject><subject>MISCELLANEOUS APPLICATIONS OF MATERIALS</subject><subject>MISCELLANEOUS COMPOSITIONS</subject><subject>NATURAL RESINS</subject><subject>PAINTS</subject><subject>PASTES OR SOLIDS FOR COLOURING OR PRINTING</subject><subject>PERFORMING OPERATIONS</subject><subject>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</subject><subject>POLISHES</subject><subject>TRANSPORTING</subject><subject>USE OF MATERIALS THEREFOR</subject><subject>WOODSTAINS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNAPCPJ3dg0OVnDzD1LwdfQLdXN0DgkN8vRzV3BU8PV0DvJ38wn1dPF0VnBxDfN0duVhYE1LzClO5YXS3AzKbq4hzh66qQX58anFBYnJqXmpJfGhwUYGRiYmhmZmxhaOhsbEqQIAowEm9w</recordid><startdate>20241219</startdate><enddate>20241219</enddate><creator>ZUILHOF, Johannes Teunis</creator><creator>SCHERES, Luc</creator><creator>RIJO DA COSTA CARVALHO, Rui Pedro</creator><creator>KNOBEN, Wout</creator><scope>EVB</scope></search><sort><creationdate>20241219</creationdate><title>PROCESS FOR MANUFACTURING A MICROFLUIDIC DEVICE</title><author>ZUILHOF, Johannes Teunis ; SCHERES, Luc ; RIJO DA COSTA CARVALHO, Rui Pedro ; KNOBEN, Wout</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2024416638A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2024</creationdate><topic>ADHESIVES</topic><topic>CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE</topic><topic>CHEMICAL PAINT OR INK REMOVERS</topic><topic>CHEMISTRY</topic><topic>COATING COMPOSITIONS, e.g. PAINTS, VARNISHES ORLACQUERS</topic><topic>CORRECTING FLUIDS</topic><topic>DYES</topic><topic>FILLING PASTES</topic><topic>INKS</topic><topic>LAYERED PRODUCTS</topic><topic>LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT ORNON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM</topic><topic>METALLURGY</topic><topic>MISCELLANEOUS APPLICATIONS OF MATERIALS</topic><topic>MISCELLANEOUS COMPOSITIONS</topic><topic>NATURAL RESINS</topic><topic>PAINTS</topic><topic>PASTES OR SOLIDS FOR COLOURING OR PRINTING</topic><topic>PERFORMING OPERATIONS</topic><topic>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</topic><topic>POLISHES</topic><topic>TRANSPORTING</topic><topic>USE OF MATERIALS THEREFOR</topic><topic>WOODSTAINS</topic><toplevel>online_resources</toplevel><creatorcontrib>ZUILHOF, Johannes Teunis</creatorcontrib><creatorcontrib>SCHERES, Luc</creatorcontrib><creatorcontrib>RIJO DA COSTA CARVALHO, Rui Pedro</creatorcontrib><creatorcontrib>KNOBEN, Wout</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ZUILHOF, Johannes Teunis</au><au>SCHERES, Luc</au><au>RIJO DA COSTA CARVALHO, Rui Pedro</au><au>KNOBEN, Wout</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESS FOR MANUFACTURING A MICROFLUIDIC DEVICE</title><date>2024-12-19</date><risdate>2024</risdate><abstract>A process for manufacturing a microfluidic device including:a) providing a first substrate having a first surface including a first flat part and a first concavity and a second substrate having a second surface including a second flat part and an optional second concavity,b) coating at least one of the first surface and the second surface with a coating composition includingi) a monomer A including one moiety represented by CH2=CR1R2 wherein R1 represents H or CH3 and R2 represents -COO- or -CONH-, and a non-ionic hydrophilic moiety;ii) a monomer B including two or more moieties represented by CH2=CR1R2 wherein R1 represents H or CH3 and R2 represents -COO- or -CONH-, and a non-ionic hydrophilic moiety;iii) optionally a photoinitiator;iv) optionally a diluent;c) evaporating the diluent if present, and forming a liquid coating;d) contacting the substrates so as to obtain an assembly in which the first flat part and the second flat part contact each other to define a microfluidic structure between the first and the second surfaces, wherein the microfluidic structure includes the first concavity and the optional second concavity; ande) at least partially irradiating the assembly with light having a wavelength between 200 and 800 nm to crosslink the liquid coating to bond the first flat part and the second flat part and obtain a crosslinked coating on at least the first concavity.A microfluidic device having two parts bonded together with a crosslinked composition and a channel which includes at least partly the crosslinked composition as a coating.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_US2024416638A1
source esp@cenet
subjects ADHESIVES
CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
CHEMICAL PAINT OR INK REMOVERS
CHEMISTRY
COATING COMPOSITIONS, e.g. PAINTS, VARNISHES ORLACQUERS
CORRECTING FLUIDS
DYES
FILLING PASTES
INKS
LAYERED PRODUCTS
LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT ORNON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
METALLURGY
MISCELLANEOUS APPLICATIONS OF MATERIALS
MISCELLANEOUS COMPOSITIONS
NATURAL RESINS
PAINTS
PASTES OR SOLIDS FOR COLOURING OR PRINTING
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
POLISHES
TRANSPORTING
USE OF MATERIALS THEREFOR
WOODSTAINS
title PROCESS FOR MANUFACTURING A MICROFLUIDIC DEVICE
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-26T18%3A35%3A58IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=ZUILHOF,%20Johannes%20Teunis&rft.date=2024-12-19&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS2024416638A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true