METHODS AND COMPOSITIONS FOR IMPROVED SNP DISCRIMINATION

Compositions and methods for improved SNP discrimination are provided. An exemplary composition comprises a programmable nuclease and a non-naturally occurring guide nucleic acid that hybridizes to a target nucleic acid, or segment thereof, comprising at least one single-nucleotide polymorphism (SNP...

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Hauptverfasser: BROUGHTON, James Paul, HENDRIKS, Carley Gelenter, CHEN, Janice Sha, CHING, Jesus, MCKAY, Bridget Ann Paine, FASCHING, Clare Louise
Format: Patent
Sprache:eng
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