FORMULATIONS FOR TRANSDERMAL ADMINISTRATION OF ACTIVE AGENTS

FORMULATIONS FOR TRANSDERMAL ADMINISTRATION OF ACTIVE AGENTS

The present disclosure relates to a formulations and methods for transdermal delivery of a medicament through the skin of a subject. In aspects, the formulation comprises a therapeutically effective amount of a medicament and a penetrant portion in which the penetrant portion comprises: a phospholip...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HARBERT, CHARLES A, BEAL, RYAN, RICE, AUDRENE, SAND, BRANDON, FITZSIMMONS, NATHAN, KOTHARY, PARSHVA
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present disclosure relates to a formulations and methods for transdermal delivery of a medicament through the skin of a subject. In aspects, the formulation comprises a therapeutically effective amount of a medicament and a penetrant portion in which the penetrant portion comprises: a phospholipid, a fatty acid ester formed from a low molecular weight alcohol, and a long-chain fatty acid. In some embodiments, the penetrant portion further comprises one or more of a viscosity-improving agents, a penetration enhancer, and an emulsifier.