Pharmaceutical Peptide Compositions and Methods of Preparation Thereof

Disclosed herein is a stabilized peptide composition that includes a glucagon-like peptide and a stabilizer. The stabilizer may be a stabilizing peptide having the same amino acid sequence as the glucagon-like peptide except the stabilizing peptide has at least one sequence alteration that may be a...

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Hauptverfasser: Banasiak, Katarzyna, Downes, Claire, Fitzgerald, Michael Paul, Carr, Paul, sivadas, Neeraj
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creator Banasiak, Katarzyna
Downes, Claire
Fitzgerald, Michael Paul
Carr, Paul
sivadas, Neeraj
description Disclosed herein is a stabilized peptide composition that includes a glucagon-like peptide and a stabilizer. The stabilizer may be a stabilizing peptide having the same amino acid sequence as the glucagon-like peptide except the stabilizing peptide has at least one sequence alteration that may be a truncation, a deletion, a substitution and/or an insertion. Also disclosed are methods for making the stabilized peptide composition and its use for treating patients in need thereof.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Pharmaceutical Peptide Compositions and Methods of Preparation Thereof
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