BENZIMIDAZOLE PYRIDINE DERIVATIVES

The invention relates to a compound of formula (I)wherein A1, R1, R2, R3, R4 and R5 are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament for treatment of indications associated with Salt-inducible kinases (SIK) such as of rheumatoid arthritis,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KREIS, Lukas, LUK, Kin-Chun Thomas, GROEBKE ZBINDEN, Katrin, HAAP, Wolfgang, MISCHKE, Steven Gregory, PFLIEGER, Philippe
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to a compound of formula (I)wherein A1, R1, R2, R3, R4 and R5 are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament for treatment of indications associated with Salt-inducible kinases (SIK) such as of rheumatoid arthritis, juvenile rheumatoid arthritis, non-alcoholic steatohepatitis (NASH), primary sclerosing cholangitis, giant cell vasculitis, inflammatory bowel diseases (IBD), atherosclerosis, type 2 diabetes or glomerulonephritis.