ANTI-PD-L1 AND IL-2 CYTOKINES

The present invention relates to anti-PD-L1 antibodies, bispecific antibodies containing one domain with specificity to PD-L1, and to immunocytokines comprising an anti-PD-L1 antibody fused to a cytokine, such as IL-2. The present invention also provides methods of treatment, uses and pharmaceutical...

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Bibliographische Detailangaben
Hauptverfasser: GALLAGHER, Thomas, SANDY, Nikole, GERMASCHEWSKI, Volker, ARKINSTALL, Stephen John, GILLIES, Stephen Douglas, VAN KRINKS, Cassandra, CAMPBELL, Jamie, KIRBY, Ian, DEANTONIO, Cecilia, KOSMAC, Miha
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to anti-PD-L1 antibodies, bispecific antibodies containing one domain with specificity to PD-L1, and to immunocytokines comprising an anti-PD-L1 antibody fused to a cytokine, such as IL-2. The present invention also provides methods of treatment, uses and pharmaceutical compositions comprising the antibodies, bispecific antibodies and immunocytokines.