RECOMBINANT ANTIGEN FOR INDUCING AN IMMUNE RESPONSE AGAINST THE ZIKA VIRUS

Recombinant chimeric antigen containing a polypeptide comprises amino acids 2 to 104 of the zika virus capsid protein or a polypeptide with an amino acid sequence with at least 90% identity with such capsid protein region. Vaccine composition that comprises such recombinant chimeric antigen and a ph...

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Hauptverfasser: ROMERO FERNÁNDEZ, Yaremis, BRUNO DARDER, Andy Jesús, PÉREZ FUENTES, Yusleidi de la Caridad, HERMIDA CRUZ, Lisset, GUILLEN NIETO, Gerardo Enrique, COBAS ACOSTA, Karem, SUZARTE PORTAL, Edith, VALDES PRADO, Iris, LAZO VAZQUEZ, Laura, GIL GONZÁLEZ, Lázaro
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creator ROMERO FERNÁNDEZ, Yaremis
BRUNO DARDER, Andy Jesús
PÉREZ FUENTES, Yusleidi de la Caridad
HERMIDA CRUZ, Lisset
GUILLEN NIETO, Gerardo Enrique
COBAS ACOSTA, Karem
SUZARTE PORTAL, Edith
VALDES PRADO, Iris
LAZO VAZQUEZ, Laura
GIL GONZÁLEZ, Lázaro
description Recombinant chimeric antigen containing a polypeptide comprises amino acids 2 to 104 of the zika virus capsid protein or a polypeptide with an amino acid sequence with at least 90% identity with such capsid protein region. Vaccine composition that comprises such recombinant chimeric antigen and a pharmaceutically approved adjuvant. Use of the recombinant chimeric antigen containing a polypeptide comprises amino acids 2 to 104 of the zika virus capsid protein or a polypeptide with an amino acid sequence with at least 90% identity with such capsid protein region, for manufacturing a medicament for the induction of immune response against zika virus. The invention revels also a method for the induction of immune response against zika virus wherein this recombinant chimeric antigen is administered.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title RECOMBINANT ANTIGEN FOR INDUCING AN IMMUNE RESPONSE AGAINST THE ZIKA VIRUS
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