IL-12/IL-18 SUPERKINES

Provided herein are novel soluble-fusion protein complexes comprising interleukin 18 (IL-18) and interleukin 12 (IL-12) polypeptide domains. Also provided are compositions comprising the soluble-fusion protein complexes as well as methods of using the soluble-fusion protein complexes.

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Bibliographische Detailangaben
Hauptverfasser:	Tanaka, Shiho, Saxena, Manju, Olson, Clifford Anders, Higashide, Wendy
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Provided herein are novel soluble-fusion protein complexes comprising interleukin 18 (IL-18) and interleukin 12 (IL-12) polypeptide domains. Also provided are compositions comprising the soluble-fusion protein complexes as well as methods of using the soluble-fusion protein complexes.