FORMULATIONS OF FACTOR VIII CHIMERIC PROTEINS AND USES THEREOF

FORMULATIONS OF FACTOR VIII CHIMERIC PROTEINS AND USES THEREOF

The present disclosure provides pharmaceutical compositions of a chimeric protein comprising a factor VIII (FVIII) polypeptide and a von Willebrand factor (VWF) polypeptide. Also disclosed are pharmaceutical kits and methods of using the disclosed pharmaceutical compositions to treat hemophilia A.

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: CARLAGE, Tyler, MCCOY, Timothy R, MAULDIN, Randall, TAZI, Loubna Mzaalak
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator CARLAGE, Tyler
MCCOY, Timothy R
MAULDIN, Randall
TAZI, Loubna Mzaalak
description The present disclosure provides pharmaceutical compositions of a chimeric protein comprising a factor VIII (FVIII) polypeptide and a von Willebrand factor (VWF) polypeptide. Also disclosed are pharmaceutical kits and methods of using the disclosed pharmaceutical compositions to treat hemophilia A.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US2024287158A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US2024287158A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US2024287158A13</originalsourceid><addsrcrecordid>eNrjZLBz8w_yDfVxDPH09wtW8HdTcHN0DvEPUgjz9PRUcPbw9HUN8nRWCAjyD3H1BCpw9HNRCA12DVYI8XANcvV342FgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8aHBRgZGJkYW5oamFo6GxsSpAgAMuCsn</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>FORMULATIONS OF FACTOR VIII CHIMERIC PROTEINS AND USES THEREOF</title><source>esp@cenet</source><creator>CARLAGE, Tyler ; MCCOY, Timothy R ; MAULDIN, Randall ; TAZI, Loubna Mzaalak</creator><creatorcontrib>CARLAGE, Tyler ; MCCOY, Timothy R ; MAULDIN, Randall ; TAZI, Loubna Mzaalak</creatorcontrib><description>The present disclosure provides pharmaceutical compositions of a chimeric protein comprising a factor VIII (FVIII) polypeptide and a von Willebrand factor (VWF) polypeptide. Also disclosed are pharmaceutical kits and methods of using the disclosed pharmaceutical compositions to treat hemophilia A.</description><language>eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20240829&amp;DB=EPODOC&amp;CC=US&amp;NR=2024287158A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76516</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20240829&amp;DB=EPODOC&amp;CC=US&amp;NR=2024287158A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CARLAGE, Tyler</creatorcontrib><creatorcontrib>MCCOY, Timothy R</creatorcontrib><creatorcontrib>MAULDIN, Randall</creatorcontrib><creatorcontrib>TAZI, Loubna Mzaalak</creatorcontrib><title>FORMULATIONS OF FACTOR VIII CHIMERIC PROTEINS AND USES THEREOF</title><description>The present disclosure provides pharmaceutical compositions of a chimeric protein comprising a factor VIII (FVIII) polypeptide and a von Willebrand factor (VWF) polypeptide. Also disclosed are pharmaceutical kits and methods of using the disclosed pharmaceutical compositions to treat hemophilia A.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLBz8w_yDfVxDPH09wtW8HdTcHN0DvEPUgjz9PRUcPbw9HUN8nRWCAjyD3H1BCpw9HNRCA12DVYI8XANcvV342FgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8aHBRgZGJkYW5oamFo6GxsSpAgAMuCsn</recordid><startdate>20240829</startdate><enddate>20240829</enddate><creator>CARLAGE, Tyler</creator><creator>MCCOY, Timothy R</creator><creator>MAULDIN, Randall</creator><creator>TAZI, Loubna Mzaalak</creator><scope>EVB</scope></search><sort><creationdate>20240829</creationdate><title>FORMULATIONS OF FACTOR VIII CHIMERIC PROTEINS AND USES THEREOF</title><author>CARLAGE, Tyler ; MCCOY, Timothy R ; MAULDIN, Randall ; TAZI, Loubna Mzaalak</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2024287158A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>CARLAGE, Tyler</creatorcontrib><creatorcontrib>MCCOY, Timothy R</creatorcontrib><creatorcontrib>MAULDIN, Randall</creatorcontrib><creatorcontrib>TAZI, Loubna Mzaalak</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CARLAGE, Tyler</au><au>MCCOY, Timothy R</au><au>MAULDIN, Randall</au><au>TAZI, Loubna Mzaalak</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>FORMULATIONS OF FACTOR VIII CHIMERIC PROTEINS AND USES THEREOF</title><date>2024-08-29</date><risdate>2024</risdate><abstract>The present disclosure provides pharmaceutical compositions of a chimeric protein comprising a factor VIII (FVIII) polypeptide and a von Willebrand factor (VWF) polypeptide. Also disclosed are pharmaceutical kits and methods of using the disclosed pharmaceutical compositions to treat hemophilia A.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_US2024287158A1
source esp@cenet
subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title FORMULATIONS OF FACTOR VIII CHIMERIC PROTEINS AND USES THEREOF
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-15T10%3A22%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=CARLAGE,%20Tyler&rft.date=2024-08-29&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS2024287158A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true