METHOD TO PRODUCE RETINYL ACETATE

The present invention is related to a novel process for production of retinyl acetate in a host cell, particularly oleaginous yeast such as e.g. Yarrowia, wherein the product purity could be increased with reduction of unwanted side-products. Particularly, the novel process comprises fermentation in...

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Bibliographische Detailangaben
Hauptverfasser: VYAS, Valmik Kanubhai, LAM, Ethan, HOUSTON, Peter Louis, SYMBOR-NAGRABSKA, Anna, FARRELL, Christopher Mark, DOTEN, Reed Chadbourne
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention is related to a novel process for production of retinyl acetate in a host cell, particularly oleaginous yeast such as e.g. Yarrowia, wherein the product purity could be increased with reduction of unwanted side-products. Particularly, the novel process comprises fermentation in the presence of ethanol, such as e.g. in a fed-batch fermentation process. Such process is especially useful in a biotechnological process for production of vitamin A.