Infusion Systems for In-Line Disinfection of Infusates and Methods Thereof

An infusion system for in-line disinfection of a prepared infusate with UV light can include a vascular access device ("VAD") and a UV light ring. The VAD can include an intracorporeal conduit, one or more extracorporeal conduits fluidly connected to the intracorporeal conduit, a hub between a proximal portion of the intracorporeal conduit and one or more respective distal portions of the one-or-more extracorporeal conduits, and one or more respective connectors of the one-or-more extracorporeal conduits. The intracorporeal conduit is configured to be percutaneously inserted into a patient, and the extracorporeal conduit is configured to remain outside a body of the patient. The UV light ring can be configured to encircle a portion of an infusion lumen of the VAD and irradiate the prepared infusate within the infusion lumen with the UV light for infusing a disinfected infusate into the patient during an infusion of the patient.